GH Receptor Exon 3 Genotype and Echocardiographic Abnormalities in Patients With Active Acromegaly

Background: The GH receptor (GHR) exon 3 polymorphism occurs at a genomic level. Approximately 50-60% of the population is homozygous for the exon-3 containing genotype (+3/+3), 30-40% are heterozygous (+3/-3) and 10-20% are homozygous for the exon-3 lacking genotype (-3/-3). Some studies suggest th...

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Detalles Bibliográficos
Autores principales: Serrano, Karla, Espinosa, Etual, Marrero-Rodríguez, Daniel, Almeida, Eduardo, Silva-Roman, Gloria, Peña-Martinez, Eduardo, Sosa, Ernesto, Mercado, Moises
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Neuroendocrinology and Pituitary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090329/
http://dx.doi.org/10.1210/jendso/bvab048.1311

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