Persistent COUP-TFII Expression Underlies the Myopathy and Impaired Muscle Regeneration Observed in Resistance to Thyroid Hormone-Alpha

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Myopathic changes, including muscular dystrophy and weakness, are commonly described in hypothyroid and hyperthyroid patients. Thyroid hormone signaling, via activation of thyroid nuclear receptor alpha (THRA), plays an essential role in maintaining muscle mass, function, and regeneration. A mouse m...

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Detalles Bibliográficos
Autores principales: Aguiari, Paola, Liu, Yan-Yun, Petrosyan, Astgik, Cheng, Sheue-Yann, Brent, Gregory A, Perin, Laura, Milanesi, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Steroid Hormones and Receptors
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090385/
http://dx.doi.org/10.1210/jendso/bvab048.1658
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