DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption

BACKGROUND: Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland. METHODS: DEHP (vehicle, 50 mg/kg, and 500 mg/kg) was admini...

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Detalles Bibliográficos
Autores principales: Kim, Min Joo, Kim, Hwan Hee, Song, Young Shin, Kim, Ok-Hee, Choi, Kyungho, Kim, Sujin, Oh, Byung-Chul, Park, Young Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Endocrine Society 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090463/
https://www.ncbi.nlm.nih.gov/pubmed/33789034
http://dx.doi.org/10.3803/EnM.2020.920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090463/
https://www.ncbi.nlm.nih.gov/pubmed/33789034
http://dx.doi.org/10.3803/EnM.2020.920

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