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Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri

Introduction: Thyroid cancer prevalence has increased significantly in recent years, including in Algeria, which primarily concerned microcarcinoma making 30 to 50% of new diagnosed cases. Despite its good prognosis, its management remains highly controversial and debated. We aim to describe charact...

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Autores principales: Kaouache, Nadjib, Billel, Zouraghen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090490/
http://dx.doi.org/10.1210/jendso/bvab048.1751
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author Kaouache, Nadjib
Billel, Zouraghen
author_facet Kaouache, Nadjib
Billel, Zouraghen
author_sort Kaouache, Nadjib
collection PubMed
description Introduction: Thyroid cancer prevalence has increased significantly in recent years, including in Algeria, which primarily concerned microcarcinoma making 30 to 50% of new diagnosed cases. Despite its good prognosis, its management remains highly controversial and debated. We aim to describe characteristics of thyroid microcarcinoma in a series from eastern Algeria monitored in the endocrinology department of Constantine University Hospital and to report the difficulties pertaining to its management. Patients and Methods: A descriptive retrospective study including patients followed and monitored in the thyroid cancer register in the endocrinology department of Constantine University Hospital during the period between January 2015 and December 2018. Results: Of 70 cases of thyroid microcarcinomas, mean age was 44 years [17-84 years] and 94% were women. 94% of the cases were papillary micro carcinomas; the two most frequent variants were the classic papillary and the vesicular variant of papillary carcinoma in 80% of cases. The diagnosis was made following a multi-nodular goiter exploration in 60% and thyroid function was normal in 50%. Moltifocality and bilaterality were reported in 27% and 5.71% of cases respectively. The most common surgical procedure was total thyroidectomy (96%), without lymph node dissection (86%). Classification of the initial risk was impossible due to the insufficient data in 28% of cases. 52% of patients received RAI therapy and 81% were in complete remission. Conclusion: Thyroid micro carcinoma has a good prognosis; however, its management faces several issues, mainly the stratification of risk which would be a source of overtreatment.
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spelling pubmed-80904902021-05-05 Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri Kaouache, Nadjib Billel, Zouraghen J Endocr Soc Thyroid Introduction: Thyroid cancer prevalence has increased significantly in recent years, including in Algeria, which primarily concerned microcarcinoma making 30 to 50% of new diagnosed cases. Despite its good prognosis, its management remains highly controversial and debated. We aim to describe characteristics of thyroid microcarcinoma in a series from eastern Algeria monitored in the endocrinology department of Constantine University Hospital and to report the difficulties pertaining to its management. Patients and Methods: A descriptive retrospective study including patients followed and monitored in the thyroid cancer register in the endocrinology department of Constantine University Hospital during the period between January 2015 and December 2018. Results: Of 70 cases of thyroid microcarcinomas, mean age was 44 years [17-84 years] and 94% were women. 94% of the cases were papillary micro carcinomas; the two most frequent variants were the classic papillary and the vesicular variant of papillary carcinoma in 80% of cases. The diagnosis was made following a multi-nodular goiter exploration in 60% and thyroid function was normal in 50%. Moltifocality and bilaterality were reported in 27% and 5.71% of cases respectively. The most common surgical procedure was total thyroidectomy (96%), without lymph node dissection (86%). Classification of the initial risk was impossible due to the insufficient data in 28% of cases. 52% of patients received RAI therapy and 81% were in complete remission. Conclusion: Thyroid micro carcinoma has a good prognosis; however, its management faces several issues, mainly the stratification of risk which would be a source of overtreatment. Oxford University Press 2021-05-03 /pmc/articles/PMC8090490/ http://dx.doi.org/10.1210/jendso/bvab048.1751 Text en © The Author(s) 2021. Published by Oxford University Press on behalf of the Endocrine Society. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Thyroid
Kaouache, Nadjib
Billel, Zouraghen
Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title_full Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title_fullStr Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title_full_unstemmed Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title_short Characteristics and Difficulties in the Management of Thyroid Microcarcinoma in Algeri
title_sort characteristics and difficulties in the management of thyroid microcarcinoma in algeri
topic Thyroid
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090490/
http://dx.doi.org/10.1210/jendso/bvab048.1751
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