Oleanolic Acid Modulates 25-Hydroxyvitamin D(3) 1-alpha-hydroxylase in Osteoblasts and Human Mesenchymal Stem Cells

Objectives: 25-Hydroxyvitamin D(3) 1-alpha-hydroxylase (CYP27B1) catalyzes the hydroxylation of 25-hydroxyvitamin D(3) (25(OH)D(3)) to 1alpha,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), the bioactive form of vitamin D(3). Our previous studies suggested that oleanolic acid (OA), a pentacyclic triterp...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Wen-Xuan, Poon, Christina Chui-Wa, Lee, Wayne Yuk-Wai, Wong, Man-Sau
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Bone and Mineral Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090494/
http://dx.doi.org/10.1210/jendso/bvab048.482

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090494/
http://dx.doi.org/10.1210/jendso/bvab048.482

Ejemplares similares