Cargando…

Mice With Targeted Deletion of ARC Kisspeptin Exhibit Immature Gametogenesis and Impaired Fertility

Hypothalamic kisspeptin is primarily synthesized in two discrete nuclei - the anteroventral periventricular (AVPV) and the arcuate (ARC) nuclei. We have previously developed a selective, conditional ARC kisspeptin knock-out (KO) mouse line, namely the Pdyn-Cre/Kiss(fl/fl) KO mice, that exhibited nor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Nandankar, Nimisha, Negron, Ariel L, Wolfe, Andrew M, Levine, Jon E, Radovick, Sally
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Neuroendocrinology and Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090563/ http://dx.doi.org/10.1210/jendso/bvab048.1107

Ejemplares similares

RF01 | PMON44 Absence of Kisspeptin in KNDy Neurons of Mice Causes Sexually Dimorphic Metabolic Dysfunction on a High-Fat Diet
por: Nandankar, Nimisha, et al.
Publicado: (2022)

SUN-243 Deletion of KNDy Neuron-Specific KISS1 Disrupts Estrous Cyclicity and LH Pulsatility in Female Mice
por: Nandankar, Nimisha, et al.
Publicado: (2020)

FRI276 KNDy-Neuron Kisspeptin Is Dispensable For Feeding Behavior, But Critical For Energy Expenditure Leading To Metabolic Dysfunction In Female Mice
por: Nandankar, Nimisha, et al.
Publicado: (2023)

Development of a Novel Tetracycline-Inducible Kiss1-Cre Mouse Line for Temporally Controlled Gene Deletion in Kisspeptin Neurons
por: Negron, Ariel L, et al.
Publicado: (2021)

PMON53 Resistance to weight gain and obesity in mice lacking the IGF-1 receptor in GHRH neurons
por: Al-Samerria, Sarmed, et al.
Publicado: (2022)

SUN-261 Deletion of Hepatic Kisspeptin Results in Abnormal Glucose Metabolism in Female Mice
por: Aloqaily, Bahaa, et al.
Publicado: (2020)

Deficiency of arcuate nucleus kisspeptin results in postpubertal central hypogonadism
por: Nandankar, Nimisha, et al.
Publicado: (2021)

SUN-483 High-Fat Diet Suppresses Basal Lh Pulsatile Levels in Female Mice at Estrus
por: Negron, Ariel, et al.
Publicado: (2019)

THU049 Growth Hormone Treatment Reverses Deficits In POU1F1 Gene Mutation
por: Al-Samerria, Sarmed, et al.
Publicado: (2023)

SAT-410 Kisspeptin Is Required for Perinatal Testosterone Surge in Male Rats
por: Chen, Jing, et al.
Publicado: (2019)

Dissecting the Involvement of Arcuate Nucleus Kisspeptin Neurons in Puberty Onset and LH Secretion
por: Coutinho, Eulalia A, et al.
Publicado: (2021)

Expression of Kisspeptin, Neurokinin B, and Dynorphin During Pubertal Development in Female Sheep
por: Aerts, Eliana G, et al.
Publicado: (2021)

OR06-2 Kisspeptin Enhances Brain Processing of Olfactory and Visual Cues of Attraction in Men
por: Yang, Lisa, et al.
Publicado: (2019)

SAT-407 Evidence for Impaired Kisspeptin Signaling During Metabolic Stress in Female Mice
por: McCosh, Richard, et al.
Publicado: (2019)

FRI282 Sexually Dimorphic Responses Of Kisspeptin Expression To Neonatal Exposure To Estrogen In Rats
por: Marzbanabbasabadi, Behrokh, et al.
Publicado: (2023)

SAT592 Sexually Dimorphic Modulation Of Arcuate Kisspeptin Neurons Activity In Response To NPY
por: da Silva Mansano, Naira, et al.
Publicado: (2023)

FRI275 Glutamate Receptor Agonists Stimulate Kisspeptin Neurons In The Arcuate Nucleus Of The Hypothalamus
por: Bearss, Robin, et al.
Publicado: (2023)

FRI281 Sexual Dimorphism In The LH Responses To Kisspeptin And Senktide Administration In Prepubertal Mice
por: Maione, Luigi, et al.
Publicado: (2023)

SAT-409 A Novel Population of Kisspeptin Neurons in the Medial Tuberal Nucleus of the Hypothalamus in Mice
por: Stephens, Shannon, et al.
Publicado: (2019)

OR32-3 Kisspeptin- a Novel Clinical Test of Hypothalamic Function in Men with Hypogonadotrophic Hypogonadism
por: Phylactou, Maria, et al.
Publicado: (2019)

Estrogen Differentially Regulates Protein Abundance in Exosomes Released From Immortalized Kisspeptin Neurons in Vitro
por: James, Teagan, et al.
Publicado: (2021)

SAT593 Mechanism Of Kisspeptin Neuron Synchronization In Acute Brain Slices From Female Mice
por: Morris, Paul G, et al.
Publicado: (2023)

SUN-484 Effect of Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) in the Regulation of Hypothalamic Kisspeptin Expression
por: Kanasaki, Haruhiko, et al.
Publicado: (2019)

SAT-LB56 Undernutrition Reduces Transcript Abundance of Kisspeptin and Neurokinin B in Young Male Sheep
por: Shuping, Sydney L, et al.
Publicado: (2020)

RF13 | PMON133 A novel variant in an intron consensus sequence associated with familial growth hormone deficiency
por: Jee, Youn Hee, et al.
Publicado: (2022)

SAT-419 Mechanisms Underlying Glucocorticoid-Induced Suppression of Pulsatile LH: Insights from Immortalized Kisspeptin Cells
por: Tian, Katherine, et al.
Publicado: (2019)

OR16-01 The Expression of the Homeodomain Transcription Factor SIX3 within Kisspeptin Neurons Is Necessary for Reproduction in Mice
por: Lavalle, Shanna N, et al.
Publicado: (2020)

SUN-LB57 Assessing the Requirement of Arcuate Nucleus Kisspeptin Neurons in Puberty Onset and Adult LH Secretion
por: Coutinho, Eulalia A, et al.
Publicado: (2020)

Role and Mechanism of Chronic Restraint Stress in Regulating Energy Metabolism and Reproductive Function Through Hypothalamic Kisspeptin Neurons
por: Huang, Yinqiong, et al.
Publicado: (2021)

OR17-5 Kisspeptin Increases Penile Tumescence and Sexual Brain Processing in Men with Hypoactive Sexual Desire Disorder
por: Abbara, Ali, et al.
Publicado: (2022)

OR17-06 Clinical And Mechanistic Insight For The Therapeutic Potential Of Intranasal Kisspeptin Administration To Treat Reproductive Disorders In Humans
por: Mills, Edouard G, et al.
Publicado: (2023)

FRI278 Kisspeptin Neuron Projections And Expression Patterns Are Unaltered In Prenatally Androgenized Female Mice Modeling PCOS
por: Prescott, Melanie, et al.
Publicado: (2023)

SAT-421 Cell-Specific Ablation of GnRH Neurons Using Kisspeptin-Saporin in the Preoptic Area of Sheep, but Not Mice
por: Porter, Danielle, et al.
Publicado: (2019)

SUN-238 Estrogen Modulates Expression Levels of Gonadotropin-Releasing Hormone Receptor (GNRHR) in Immortalized Kisspeptin Neurons in Vitro
por: Rayzmann, Noa, et al.
Publicado: (2020)

SAT-425 NKB Signaling in the Posterodorsal Medial Amygdala Stimulates Gonadotropin Release in a Kisspeptin-Independent Manner in Female Mice
por: Fergani, Chrysanthi, et al.
Publicado: (2019)

SUN-470 The Homeodomain Transcription Factors Six3 and OTX2 Act on Mouse and Human Kisspeptin Promoters to Repress Transcription
por: Newton, Shanna, et al.
Publicado: (2019)

SAT-405 Activation of Kiss1 Neurons in the Posterodorsal Medial Amygdala Stimulates Gonadotropin Release via the Release of Kisspeptin in Female Mice
por: Fergani, Chrysanthi, et al.
Publicado: (2019)

OR17-3 Immortalized AVPV Kisspeptin Neurons Transiently Express GnRH Receptors under Specific Sex Steroid Conditions in vitro
por: Lee, Blake, et al.
Publicado: (2022)

SUN-263 In Vitro Modeling of Brain-Bone Communication: Factors Secreted from Immortalized Female Kisspeptin Neurons Modulate Gene Expression in Osteoblasts
por: James, Teagan, et al.
Publicado: (2020)

PMON54 Exosomes Isolated from Conditioned Media of Immortalized Kisspeptin Neurons Exert Diverse Effects on Central and Peripheral in Vitro Cell Models.
por: Chappell, Patrick, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ch4a84gt5nfkqud16ia8s9f83c