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GH Is a Component of SASP in Aging Tissue

Deficient GH signaling results in lifespan extension in murine and human models, while patients with uncontrolled acromegaly and transgenic mice overexpressing GH have a shorter lifespan. Colon polyp development increases with age, and also with GH excess in acromegaly. Aging is characterized by sen...

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Detalles Bibliográficos
Autores principales:	Chesnokova, Vera M, Zonis, Svetlana M, Estrada, Hannah, Barrett, Robert, Melmed, Shlomo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Neuroendocrinology and Pituitary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090645/ http://dx.doi.org/10.1210/jendso/bvab048.1099

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