The rs2442598 Polymorphism in ANGPT-2 Gene Is Associated With Risk for Diabetic Retinopathy in Patients With Type 1 Diabetes Mellitus From a Brazilian Population

Introduction: Angiopoietin-2 (ANGPT-2) is a member of a growth factor family that binds to the endothelial receptor tyrosine kinase 2 and regulates vascular development and function. Under hyperglycemic conditions, ANGPT-2 is upregulated and leads to vascular destabilization, pericyte dropout, and a...

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Detalles Bibliográficos
Autores principales: Dieter, Cristine, Lemos, Natália Emerim, Canani, Luis Henrique, Bauer, Andrea C, Crispim, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Genetics and Development (including Gene Regulation)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090649/
http://dx.doi.org/10.1210/jendso/bvab048.1045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090649/
http://dx.doi.org/10.1210/jendso/bvab048.1045

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