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Expression of IGF-1, IGF-1 Receptor and Growth Hormone Receptor in Hepatic Tissue in Adults Across the Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)
Background: Obesity is a state of relative growth hormone (GH) and insulin-like growth factor-1 (IGF-1) deficiency, and the GH/IGF-1 axis has been implicated in the pathophysiology of nonalcoholic fatty liver disease (NAFLD) and the progression to steatohepatitis (NASH) in preclinical models and hum...
Autores principales: | Dichtel, Laura E, Subudhi, Sonu, Drescher, Hannah, Bartsch, Lea, Osganian, Stephanie, Chicote, Mark, Masia, Ricard, Bredella, Miriam, Bhatia, Sangeeta, Lauer, Georg, Miller, Karen Klahr, Corey, Kathleen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090657/ http://dx.doi.org/10.1210/jendso/bvab048.1097 |
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