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Differential Expression of Estrogen Receptors in the Hypothalamus Underlies the Bimodal Effects of Estradiol on Luteinizing Hormone Release

Low 17β-estradiol (E2) levels suppress luteinizing hormone (LH) release, while high E(2) stimulates an LH surge in the positive-feedback required for ovulation. Kisspeptin (Kp) neurons in the anteroventral periventricular (AVPV) and arcuate (ARC) nuclei of hypothalamus have been implicated in E2 pos...

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Detalles Bibliográficos
Autores principales: Henriques, Patricia Costa, Aquino, Nayara Soares Sena, Araújo-Lopes, Roberta, Silva, Juneo Freitas, Coimbra, Candido Celso, Franci, Celso Rodrigues, Szawka, Raphael Escorsim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090696/
http://dx.doi.org/10.1210/jendso/bvab048.1092