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Probiotic Supplementation with Lactobacillus plantarum 299v Lowers Systemic Inflammation, Reduces Islet ER Stress and Prevents Type 1 Diabetes in BioBreeding Rats
Type 1 diabetes (T1D) is an autoimmune disease characterized by destruction of the pancreatic β-cells. T1D pathogenesis has a strong genetic basis. However, in recent decades, the prevalence of high-risk HLA haplotypes among new diagnoses has declined, the age of onset has decreased, and T1D inciden...
Autores principales: | Sargin, Pinar, Ciecko, Ashley E, Dew, Kristen, Rhonda, Geoffrey, Jia, Shuang, Laib, Tyler, Roethle, Mark F, Hessner, Martin J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090711/ http://dx.doi.org/10.1210/jendso/bvab048.1350 |
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