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Mild Maternal Undernutrition Results in a Premature Neonatal Leptin Surge that Promotes Resistance in Male Offspring to a High Fat Diet
Malnutrition alters leptin signaling, resulting in dysregulation of pituitary somatotropes that may be sex-specific. We reported sex differences in acute fasting responses with reductions in serum leptin in males, but not females (1). Maternal undernutrition can also alter the neonatal leptin surge...
Autores principales: | Miles, Tiffany K, Allensworth, Melody Lyn, Moreira, Ana Rita Silva, Odle, Angela Katherine, Haney, Anessa, Lagasse, Alexandra, MacNicol, Angus M, Childs, Gwen V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090743/ http://dx.doi.org/10.1210/jendso/bvab048.1109 |
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