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Coping with the calcium overload caused by cell injury: ER to the rescue

Cells maintain their cytosolic calcium (Ca(2+)) in nanomolar range and use controlled increase in Ca(2+) for intracellular signaling. With the extracellular Ca(2+) in the millimolar range, there is a steep Ca(2+) gradient across the plasma membrane (PM). Thus, injury that damages PM, leads to a cyto...

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Detalles Bibliográficos
Autores principales: Chandra, Goutam, Mázala, Davi A. G., Jaiswal, Jyoti K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shared Science Publishers OG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090859/
https://www.ncbi.nlm.nih.gov/pubmed/33987529
http://dx.doi.org/10.15698/cst2021.05.249

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