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Coping with the calcium overload caused by cell injury: ER to the rescue
Cells maintain their cytosolic calcium (Ca(2+)) in nanomolar range and use controlled increase in Ca(2+) for intracellular signaling. With the extracellular Ca(2+) in the millimolar range, there is a steep Ca(2+) gradient across the plasma membrane (PM). Thus, injury that damages PM, leads to a cyto...
Autores principales: | Chandra, Goutam, Mázala, Davi A. G., Jaiswal, Jyoti K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shared Science Publishers OG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090859/ https://www.ncbi.nlm.nih.gov/pubmed/33987529 http://dx.doi.org/10.15698/cst2021.05.249 |
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