Cargando…

Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics

Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly influenced by the way human beings interact with...

Descripción completa

Detalles Bibliográficos
Autores principales: Al-Salihi, Suhad A. A., Alberti, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090910/
https://www.ncbi.nlm.nih.gov/pubmed/33939136
http://dx.doi.org/10.1007/s13659-021-00306-z
_version_ 1783687385533382656
author Al-Salihi, Suhad A. A.
Alberti, Fabrizio
author_facet Al-Salihi, Suhad A. A.
Alberti, Fabrizio
author_sort Al-Salihi, Suhad A. A.
collection PubMed
description Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly influenced by the way human beings interact with the reservoirs, especially the animal ones. In our review we will consider the evolutionary and the ecological scales of such infections and their consequences on the public health, with a focus on the pathogenic influenza A virus. The nutraceutical properties of fungal and plant terpene-like molecules will be linked to their ability to lessen the symptoms of viral infections and shed light on their potential use in the development of new drugs. New challenging methods in antiviral discovery will also be discussed in this review. The authors believe that pharmacognosy is the “wave of future pharmaceuticals”, as it can be continually produced and scaled up under eco-friendly requirements. Further diagnostic methods and strategies however are required to standardise those naturally occurring resources.
format Online
Article
Text
id pubmed-8090910
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer Singapore
record_format MEDLINE/PubMed
spelling pubmed-80909102021-05-03 Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics Al-Salihi, Suhad A. A. Alberti, Fabrizio Nat Prod Bioprospect Review Since the olden times, infectious diseases have largely affected human existence. The newly emerged infections are excessively caused by viruses that are largely associated with mammal reservoirs. The casualties of these emergencies are significantly influenced by the way human beings interact with the reservoirs, especially the animal ones. In our review we will consider the evolutionary and the ecological scales of such infections and their consequences on the public health, with a focus on the pathogenic influenza A virus. The nutraceutical properties of fungal and plant terpene-like molecules will be linked to their ability to lessen the symptoms of viral infections and shed light on their potential use in the development of new drugs. New challenging methods in antiviral discovery will also be discussed in this review. The authors believe that pharmacognosy is the “wave of future pharmaceuticals”, as it can be continually produced and scaled up under eco-friendly requirements. Further diagnostic methods and strategies however are required to standardise those naturally occurring resources. Springer Singapore 2021-05-03 /pmc/articles/PMC8090910/ /pubmed/33939136 http://dx.doi.org/10.1007/s13659-021-00306-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Al-Salihi, Suhad A. A.
Alberti, Fabrizio
Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title_full Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title_fullStr Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title_full_unstemmed Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title_short Naturally Occurring Terpenes: A Promising Class of Organic Molecules to Address Influenza Pandemics
title_sort naturally occurring terpenes: a promising class of organic molecules to address influenza pandemics
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090910/
https://www.ncbi.nlm.nih.gov/pubmed/33939136
http://dx.doi.org/10.1007/s13659-021-00306-z
work_keys_str_mv AT alsalihisuhadaa naturallyoccurringterpenesapromisingclassoforganicmoleculestoaddressinfluenzapandemics
AT albertifabrizio naturallyoccurringterpenesapromisingclassoforganicmoleculestoaddressinfluenzapandemics