Cargando…
Identification of lysosome‐targeting drugs with anti‐inflammatory activity as potential invasion inhibitors of treatment resistant HER2 positive cancers
PURPOSE: Most HER2 positive invasive cancers are either intrinsic non-responsive or develop resistance when treated with 1st line HER2 targeting drugs. Both 1st and 2nd line treatments of HER2 positive cancers are aimed at targeting the HER2 receptor directly, thereby strongly limiting the treatment...
Autores principales: | Hansen, Malene Bredahl, Postol, Maria, Tvingsholm, Siri, Nielsen, Inger Ødum, Dietrich, Tiina Naumanen, Puustinen, Pietri, Maeda, Kenji, Dinant, Christoffel, Strauss, Robert, Egan, David, Jäättelä, Marja, Kallunki, Tuula |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8090911/ https://www.ncbi.nlm.nih.gov/pubmed/33939112 http://dx.doi.org/10.1007/s13402-021-00603-2 |
Ejemplares similares
-
Let-7 microRNA controls invasion-promoting lysosomal changes via the oncogenic transcription factor myeloid zinc finger-1
por: Tvingsholm, Siri Amanda, et al.
Publicado: (2018) -
KIAA1524/CIP2A promotes cancer growth by coordinating the activities of MTORC1 and MYC
por: Puustinen, Pietri, et al.
Publicado: (2014) -
How to Choose the Right Inducible Gene Expression System for Mammalian Studies?
por: Kallunki, Tuula, et al.
Publicado: (2019) -
Ursolic Acid Impairs Cellular Lipid Homeostasis and Lysosomal Membrane Integrity in Breast Carcinoma Cells
por: Fogde, Ditte L., et al.
Publicado: (2022) -
CIP2A oncoprotein controls cell growth and autophagy through mTORC1 activation
por: Puustinen, Pietri, et al.
Publicado: (2014)