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Caspase inhibition prolongs inflammation by promoting a signaling complex with activated RIPK1
Activation of inflammation by lipopolysaccharide (LPS) is an important innate immune response. Here we investigated the contribution of caspases to the LPS-mediated inflammatory response and discovered distinctive temporal roles of RIPK1 in mediating proinflammatory cytokine production when caspases...
Autores principales: | Huang, Xinyue, Tan, Shuixia, Li, Yanxia, Cao, Shuangyi, Li, Xingyan, Pan, Heling, Shan, Bing, Qian, Lihui, Yuan, Junying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091129/ https://www.ncbi.nlm.nih.gov/pubmed/33914027 http://dx.doi.org/10.1083/jcb.202007127 |
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