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Sampling strategies to evaluate the prognostic value of a new biomarker on a time-to-event end-point
BACKGROUND: The availability of large epidemiological or clinical data storing biological samples allow to study the prognostic value of novel biomarkers, but efficient designs are needed to select a subsample on which to measure them, for parsimony and economical reasons. Two-phase stratified sampl...
Autores principales: | Graziano, Francesca, Valsecchi, Maria Grazia, Rebora, Paola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091513/ https://www.ncbi.nlm.nih.gov/pubmed/33941092 http://dx.doi.org/10.1186/s12874-021-01283-0 |
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