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Lower starting dose of afatinib for the treatment of metastatic lung adenocarcinoma harboring exon 21 and exon 19 mutations

BACKGROUND: Afatinib has shown favorable response rates (RRs) and longer progression free survival (PFS) in lung cancer patients harboring EGFR mutations compared with standard platinum-based chemotherapy. However, serious adverse drug reactions (ADRs) limit the clinical application of afatinib. MET...

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Detalles Bibliográficos
Autores principales:	Chen, Yi-Chieh, Tsai, Ming-Ju, Lee, Mei-Hsuan, Kuo, Chia-Yu, Shen, Mei-Chiou, Tsai, Ying-Ming, Chen, Huang-Chi, Hung, Jen-Yu, Huang, Ming-Shyan, Chong, Inn-Wen, Yang, Chih-Jen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091516/ https://www.ncbi.nlm.nih.gov/pubmed/33941115 http://dx.doi.org/10.1186/s12885-021-08235-3

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