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Modern simulation utilities for genetic analysis

BACKGROUND: Statistical geneticists employ simulation to estimate the power of proposed studies, test new analysis tools, and evaluate properties of causal models. Although there are existing trait simulators, there is ample room for modernization. For example, most phenotype simulators are limited...

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Detalles Bibliográficos
Autores principales: Ji, Sarah S., German, Christopher A., Lange, Kenneth, Sinsheimer, Janet S., Zhou, Hua, Zhou, Jin, Sobel, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091532/
https://www.ncbi.nlm.nih.gov/pubmed/33941078
http://dx.doi.org/10.1186/s12859-021-04086-8

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