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Single-cell RNA sequencing of mouse islets exposed to proinflammatory cytokines

Exposure to proinflammatory cytokines is believed to contribute to pancreatic β-cell damage during diabetes development. Although some cytokine-mediated changes in islet gene expression are known, the heterogeneity of the response is not well-understood. After 6-h treatment with IL-1β and IFN-γ alon...

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Detalles Bibliográficos
Autores principales: Stancill, Jennifer S, Kasmani, Moujtaba Y, Khatun, Achia, Cui, Weiguo, Corbett, John A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091599/
https://www.ncbi.nlm.nih.gov/pubmed/33883217
http://dx.doi.org/10.26508/lsa.202000949