Levetiracetam versus fosphenytoin as a second-line treatment after diazepam for status epilepticus: study protocol for a multicenter non-inferiority designed randomized control trial

BACKGROUND: Status epilepticus (SE) is an emergency condition for which rapid and secured cessation is important. Phenytoin and fosphenytoin, the prodrug of phenytoin with less severe adverse effects, have been recommended as second-line treatments. However, fosphenytoin causes severe adverse events...

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Detalles Bibliográficos
Autores principales: Nakamura, Kensuke, Marushima, Aiki, Takahashi, Yuji, Kimura, Akio, Asami, Masahiro, Egawa, Satoshi, Kaneko, Junya, Kondo, Yutaka, Yonekawa, Chikara, Hoshiyama, Eisei, Yamada, Takeshi, Maruo, Kazushi, Inoue, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091776/
https://www.ncbi.nlm.nih.gov/pubmed/33934714
http://dx.doi.org/10.1186/s13063-021-05269-7

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