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Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report
INTRODUCTION: Osteopetrosis is a rare genetic bone disease caused by a functional abnormality of the osteoclasts. Until now there is no codified management for the complications of this pathology and few cases cited in the literature. PRESENTATION OF CASE: a 19-year-old adult followed in our maxillo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091886/ https://www.ncbi.nlm.nih.gov/pubmed/33996048 http://dx.doi.org/10.1016/j.amsu.2021.102296 |
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author | Raiteb, Mohamed Elmrini, Sanaa Slimani, Faiçal |
author_facet | Raiteb, Mohamed Elmrini, Sanaa Slimani, Faiçal |
author_sort | Raiteb, Mohamed |
collection | PubMed |
description | INTRODUCTION: Osteopetrosis is a rare genetic bone disease caused by a functional abnormality of the osteoclasts. Until now there is no codified management for the complications of this pathology and few cases cited in the literature. PRESENTATION OF CASE: a 19-year-old adult followed in our maxillofacial surgery department in the IBN ROCHD University Hospital for chronic osteomyelitis complicating mandibular osteopetrosis with skin fistulas. Patient operated several times. The persistence of osteomyelitis prevents the installation of a dental prosthesis and the appearance of new fistulas with continuous flow of pus alters the patient's quality of life. DISCUSSION: Osteopetrosis is a group of rare genetic diseases characterized by osteoclastic insufficiency, poor bone remodeling and increased bone density. the benign form of osteopetrosis called Albers-Schönberg disease. It is a genetically inherited autosomal dominant disease. The large number of surgical interventions and the use of antibiotics for long periods of time (risk of development of resistance) significantly reduces the quality of life of patients. We must seek other measures to improve the prognosis and codify management. CONCLUSION: In osteopetrosis, the maxillofacial surgeons should be aware about the early diagnosis and the appropriate management of the signs and prevent complications. |
format | Online Article Text |
id | pubmed-8091886 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-80918862021-05-13 Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report Raiteb, Mohamed Elmrini, Sanaa Slimani, Faiçal Ann Med Surg (Lond) Case Report INTRODUCTION: Osteopetrosis is a rare genetic bone disease caused by a functional abnormality of the osteoclasts. Until now there is no codified management for the complications of this pathology and few cases cited in the literature. PRESENTATION OF CASE: a 19-year-old adult followed in our maxillofacial surgery department in the IBN ROCHD University Hospital for chronic osteomyelitis complicating mandibular osteopetrosis with skin fistulas. Patient operated several times. The persistence of osteomyelitis prevents the installation of a dental prosthesis and the appearance of new fistulas with continuous flow of pus alters the patient's quality of life. DISCUSSION: Osteopetrosis is a group of rare genetic diseases characterized by osteoclastic insufficiency, poor bone remodeling and increased bone density. the benign form of osteopetrosis called Albers-Schönberg disease. It is a genetically inherited autosomal dominant disease. The large number of surgical interventions and the use of antibiotics for long periods of time (risk of development of resistance) significantly reduces the quality of life of patients. We must seek other measures to improve the prognosis and codify management. CONCLUSION: In osteopetrosis, the maxillofacial surgeons should be aware about the early diagnosis and the appropriate management of the signs and prevent complications. Elsevier 2021-04-20 /pmc/articles/PMC8091886/ /pubmed/33996048 http://dx.doi.org/10.1016/j.amsu.2021.102296 Text en © 2021 Published by Elsevier Ltd on behalf of IJS Publishing Group Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Raiteb, Mohamed Elmrini, Sanaa Slimani, Faiçal Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title | Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title_full | Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title_fullStr | Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title_full_unstemmed | Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title_short | Surgical management of chronic osteomyelitis with benign osteopetrosis: A case report |
title_sort | surgical management of chronic osteomyelitis with benign osteopetrosis: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091886/ https://www.ncbi.nlm.nih.gov/pubmed/33996048 http://dx.doi.org/10.1016/j.amsu.2021.102296 |
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