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Interfaces between cellular responses to DNA damage and cancer immunotherapy

The DNA damage response (DDR) fulfils essential roles to preserve genome integrity. Targeting the DDR in tumors has had remarkable success over the last decade, exemplified by the licensing of PARP inhibitors for cancer therapy. Recent studies suggest that the application of DDR inhibitors impacts o...

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Detalles Bibliográficos
Autores principales: Pilger, Domenic, Seymour, Leonard W., Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091970/
https://www.ncbi.nlm.nih.gov/pubmed/33888558
http://dx.doi.org/10.1101/gad.348314.121