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Interfaces between cellular responses to DNA damage and cancer immunotherapy
The DNA damage response (DDR) fulfils essential roles to preserve genome integrity. Targeting the DDR in tumors has had remarkable success over the last decade, exemplified by the licensing of PARP inhibitors for cancer therapy. Recent studies suggest that the application of DDR inhibitors impacts o...
Autores principales: | Pilger, Domenic, Seymour, Leonard W., Jackson, Stephen P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091970/ https://www.ncbi.nlm.nih.gov/pubmed/33888558 http://dx.doi.org/10.1101/gad.348314.121 |
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