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BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome
Histone-modifying systems play fundamental roles in gene regulation and the development of multicellular organisms. Histone modifications that are enriched at gene regulatory elements have been heavily studied, but the function of modifications found more broadly throughout the genome remains poorly...
Autores principales: | Fursova, Nadezda A., Turberfield, Anne H., Blackledge, Neil P., Findlater, Emma L., Lastuvkova, Anna, Huseyin, Miles K., Dobrinić, Paula, Klose, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8091973/ https://www.ncbi.nlm.nih.gov/pubmed/33888563 http://dx.doi.org/10.1101/gad.347005.120 |
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