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Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication

We interrogated at nucleotide resolution the spatiotemporal order of chromatin changes that occur immediately following a site-specific double-strand break (DSB) upstream of the PHO5 locus and its subsequent repair by nonhomologous end joining (NHEJ). We observed the immediate eviction of a nucleoso...

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Detalles Bibliográficos
Autores principales: Tripuraneni, Vinay, Memisoglu, Gonen, MacAlpine, Heather K., Tran, Trung Q., Zhu, Wei, Hartemink, Alexander J., Haber, James E., MacAlpine, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092003/
https://www.ncbi.nlm.nih.gov/pubmed/33811083
http://dx.doi.org/10.1101/gr.271155.120