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Local nucleosome dynamics and eviction following a double-strand break are reversible by NHEJ-mediated repair in the absence of DNA replication
We interrogated at nucleotide resolution the spatiotemporal order of chromatin changes that occur immediately following a site-specific double-strand break (DSB) upstream of the PHO5 locus and its subsequent repair by nonhomologous end joining (NHEJ). We observed the immediate eviction of a nucleoso...
Autores principales: | Tripuraneni, Vinay, Memisoglu, Gonen, MacAlpine, Heather K., Tran, Trung Q., Zhu, Wei, Hartemink, Alexander J., Haber, James E., MacAlpine, David M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092003/ https://www.ncbi.nlm.nih.gov/pubmed/33811083 http://dx.doi.org/10.1101/gr.271155.120 |
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