Cargando…
Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines
Glioblastoma, a grade IV astrocytoma, has a poor survival rate in part due to ineffective treatment options available. These tumours are heterogeneous with areas of low oxygen levels, termed hypoxic regions. Many intra-cellular signalling pathways, including DNA repair, can be altered by hypoxia. Si...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092103/ https://www.ncbi.nlm.nih.gov/pubmed/33986995 http://dx.doi.org/10.7717/peerj.11275 |