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Downregulation of both mismatch repair and non-homologous end-joining pathways in hypoxic brain tumour cell lines

Glioblastoma, a grade IV astrocytoma, has a poor survival rate in part due to ineffective treatment options available. These tumours are heterogeneous with areas of low oxygen levels, termed hypoxic regions. Many intra-cellular signalling pathways, including DNA repair, can be altered by hypoxia. Si...

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Detalles Bibliográficos
Autores principales:	Cowman, Sophie, Pizer, Barry, Sée, Violaine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2021
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092103/ https://www.ncbi.nlm.nih.gov/pubmed/33986995 http://dx.doi.org/10.7717/peerj.11275

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