Hydrogen sulfide therapy: a narrative overview of current research and possible therapeutic implications in future

Diabetic nephropathy is one of the most important comorbidities in the diabetic population. In China, more and more young patients are showing an increasing prevalence of diabetes. As a gas molecule, hydrogen sulfide (H(2)S) has some unique chemical and physiological functions. In recent years, it has been studied in various fields. These effects are manifested in the induction of renal vasodilation and anti-renal vascular fibrosis. The ball clearing function is improved. Therefore, increasing prospective studies have focused on how H(2)S protects diabetic nephropathy and how to obtain H(2)S by modern means to treat diabetic nephropathy.