Species-Specific Deamidation of RIG-I Reveals Collaborative Action between Viral and Cellular Deamidases in HSV-1 Lytic Replication

Retinoic acid-inducible gene I (RIG-I) is a sensor that recognizes cytosolic double-stranded RNA derived from microbes to induce host immune response. Viruses, such as herpesviruses, deploy diverse mechanisms to derail RIG-I-dependent innate immune defense. In this study, we discovered that mouse RI...

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Detalles Bibliográficos
Autores principales: Huang, Huichao, Zhao, Jun, Wang, Ting-Yu, Zhang, Shu, Zhou, Yuzheng, Rao, Youliang, Qin, Chao, Liu, Yongzhen, Chen, Yongheng, Xia, Zanxian, Feng, Pinghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092204/
https://www.ncbi.nlm.nih.gov/pubmed/33785613
http://dx.doi.org/10.1128/mBio.00115-21

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