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The DnaK Chaperone System Buffers the Fitness Cost of Antibiotic Resistance Mutations in Mycobacteria

Chaperones aid in protein folding and maintenance of protein integrity. In doing so, they have the unique ability to directly stabilize resistance-conferring amino acid substitutions in drug targets and to counter the stress imparted by these substitutions, thus supporting heritable antimicrobial re...

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Detalles Bibliográficos
Autores principales:	Fay, Allison, Philip, John, Saha, Priya, Hendrickson, Ronald C., Glickman, Michael S., Burns-Huang, Kristin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092207/ https://www.ncbi.nlm.nih.gov/pubmed/33785614 http://dx.doi.org/10.1128/mBio.00123-21

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