The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

JC polyomavirus (JCV), a DNA virus that leads to persistent infection in humans, is the causative agent of progressive multifocal leukoencephalopathy, a lethal brain disease that affects immunocompromised individuals. Almost nothing is currently known about how JCV infection is controlled by the inn...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiang, Cindy, Dvorkin, Steve, Chiang, Jessica J., Potter, Rachel B., Gack, Michaela U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092259/
https://www.ncbi.nlm.nih.gov/pubmed/33849980
http://dx.doi.org/10.1128/mBio.00620-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092259/
https://www.ncbi.nlm.nih.gov/pubmed/33849980
http://dx.doi.org/10.1128/mBio.00620-21

Ejemplares similares