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The Small t Antigen of JC Virus Antagonizes RIG-I-Mediated Innate Immunity by Inhibiting TRIM25’s RNA Binding Ability

JC polyomavirus (JCV), a DNA virus that leads to persistent infection in humans, is the causative agent of progressive multifocal leukoencephalopathy, a lethal brain disease that affects immunocompromised individuals. Almost nothing is currently known about how JCV infection is controlled by the inn...

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Detalles Bibliográficos
Autores principales:	Chiang, Cindy, Dvorkin, Steve, Chiang, Jessica J., Potter, Rachel B., Gack, Michaela U.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092259/ https://www.ncbi.nlm.nih.gov/pubmed/33849980 http://dx.doi.org/10.1128/mBio.00620-21

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