Molecular Basis for Bordetella pertussis Interference with Complement, Coagulation, Fibrinolytic, and Contact Activation Systems: the Cryo-EM Structure of the Vag8-C1 Inhibitor Complex

Complement, contact activation, coagulation, and fibrinolysis are serum protein cascades that need strict regulation to maintain human health. Serum glycoprotein, a C1 inhibitor (C1-INH), is a key regulator (inhibitor) of serine proteases of all the above-mentioned pathways. Recently, an autotranspo...

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Detalles Bibliográficos
Autores principales: Dhillon, Arun, Deme, Justin C., Furlong, Emily, Roem, Dorina, Jongerius, Ilse, Johnson, Steven, Lea, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092270/
https://www.ncbi.nlm.nih.gov/pubmed/33758081
http://dx.doi.org/10.1128/mBio.02823-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092270/
https://www.ncbi.nlm.nih.gov/pubmed/33758081
http://dx.doi.org/10.1128/mBio.02823-20

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