Cargando…
Extent of Cytomegalovirus Replication in the Human Host Depends on Variations of the HLA-E/UL40 Axis
Human cytomegalovirus (HCMV) may cause severe infections in lung transplant recipients (LTRs). In response to HCMV infections, a subset of NKG2C(+) NK cells expands, which limits HCMV replication and is characterized by high expression of the activating NKG2C/CD94 and absence of the inhibitory NKG2A...
Autores principales: | Vietzen, Hannes, Rückert, Timo, Hartenberger, Svenja, Honsig, Claudia, Jaksch, Peter, Geleff, Silvana, Hammer, Quirin, Romagnani, Chiara, Segura-Wang, Maia, Puchhammer-Stöckl, Elisabeth |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092275/ https://www.ncbi.nlm.nih.gov/pubmed/33727352 http://dx.doi.org/10.1128/mBio.02996-20 |
Ejemplares similares
-
Dissection of the NKG2C NK cell response against Puumala Orthohantavirus
por: Vietzen, Hannes, et al.
Publicado: (2021) -
HLA-E–restricted immune responses are crucial for the control of EBV infections and the prevention of PTLD
por: Vietzen, Hannes, et al.
Publicado: (2023) -
Analysis and Fine Specificity of the HCMV-Specific Cell-Free and Cell-Associated Antibody-Dependent Cellular Phagocytosis (ADCP) Responses in Lung Transplant Recipients
por: Eberhard, Simone, et al.
Publicado: (2021) -
Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19
por: Vietzen, Hannes, et al.
Publicado: (2021) -
High-affinity FcγRIIIa genetic variants and potent NK cell-mediated antibody-dependent cellular cytotoxicity (ADCC) responses contributing to severe COVID-19
por: Vietzen, Hannes, et al.
Publicado: (2022)