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B Lymphocytes, but Not Dendritic Cells, Efficiently HIV-1 Trans Infect Naive CD4(+) T Cells: Implications for the Viral Reservoir

Insight into the establishment and maintenance of HIV-1 infection in resting CD4(+) T cell subsets is critical for the development of therapeutics targeting the HIV-1 reservoir. Although the frequency of HIV-1 infection, as quantified by the frequency of HIV-1 DNA, is lower in CD4(+) naive T cells (...

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Detalles Bibliográficos
Autores principales: Gerberick, Abigail, DeLucia, Diana C., Piazza, Paolo, Alaoui-El-Azher, Mounia, Rinaldo, Charles R., Sluis-Cremer, Nicolas, Rappocciolo, Giovanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092276/
https://www.ncbi.nlm.nih.gov/pubmed/33688006
http://dx.doi.org/10.1128/mBio.02998-20