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Elucidating the Antiviral Mechanism of Different MARCH Factors

The membrane-associated RING-CH (MARCH) proteins belong to a family of E3 ubiquitin ligases, whose main function is to remove transmembrane proteins from the plasma membrane. Recent work has shown that the human MARCH1, 2, and 8 are antiretroviral factors that target the human immunodeficiency virus...

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Detalles Bibliográficos
Autores principales: Umthong, Supawadee, Lynch, Brian, Timilsina, Uddhav, Waxman, Brandon, Ivey, Emily B., Stavrou, Spyridon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092282/
https://www.ncbi.nlm.nih.gov/pubmed/33653895
http://dx.doi.org/10.1128/mBio.03264-20