Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of Vibrio cholerae O-Specific Polysaccharide-Specific Monoclonal Antibodies

Vibrio cholerae causes the severe diarrheal disease cholera. Clinical disease and current oral cholera vaccines generate antibody responses associated with protection. Immunity is thought to be largely mediated by lipopolysaccharide (LPS)-specific antibodies, primarily targeting the O-antigen. Howev...

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Detalles Bibliográficos
Autores principales: Kauffman, Robert C., Adekunle, Oluwaseyi, Yu, Hanyi, Cho, Alice, Nyhoff, Lindsay E., Kelly, Meagan, Harris, Jason B., Bhuiyan, Taufiqur Rahman, Qadri, Firdausi, Calderwood, Stephen B., Charles, Richelle C., Ryan, Edward T., Kong, Jun, Wrammert, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092325/
https://www.ncbi.nlm.nih.gov/pubmed/33879588
http://dx.doi.org/10.1128/mBio.03679-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092325/
https://www.ncbi.nlm.nih.gov/pubmed/33879588
http://dx.doi.org/10.1128/mBio.03679-20

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