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Impact of Immunoglobulin Isotype and Epitope on the Functional Properties of Vibrio cholerae O-Specific Polysaccharide-Specific Monoclonal Antibodies
Vibrio cholerae causes the severe diarrheal disease cholera. Clinical disease and current oral cholera vaccines generate antibody responses associated with protection. Immunity is thought to be largely mediated by lipopolysaccharide (LPS)-specific antibodies, primarily targeting the O-antigen. Howev...
Autores principales: | Kauffman, Robert C., Adekunle, Oluwaseyi, Yu, Hanyi, Cho, Alice, Nyhoff, Lindsay E., Kelly, Meagan, Harris, Jason B., Bhuiyan, Taufiqur Rahman, Qadri, Firdausi, Calderwood, Stephen B., Charles, Richelle C., Ryan, Edward T., Kong, Jun, Wrammert, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092325/ https://www.ncbi.nlm.nih.gov/pubmed/33879588 http://dx.doi.org/10.1128/mBio.03679-20 |
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