GPR182 is an endothelium-specific atypical chemokine receptor that maintains hematopoietic stem cell homeostasis

G protein–coupled receptor 182 (GPR182) has been shown to be expressed in endothelial cells; however, its ligand and physiological role has remained elusive. We found GPR182 to be expressed in microvascular and lymphatic endothelial cells of most organs and to bind with nanomolar affinity the chemok...

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Detalles Bibliográficos
Autores principales: Le Mercier, Alan, Bonnavion, Remy, Yu, Weijia, Alnouri, Mohamad Wessam, Ramas, Sophie, Zhang, Yang, Jäger, Yannick, Roquid, Kenneth Anthony, Jeong, Hyun-Woo, Sivaraj, Kishor Kumar, Cho, Haaglim, Chen, Xinyi, Strilic, Boris, Sijmonsma, Tjeerd, Adams, Ralf, Schroeder, Timm, Rieger, Michael A., Offermanns, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2021
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092405/
https://www.ncbi.nlm.nih.gov/pubmed/33875597
http://dx.doi.org/10.1073/pnas.2021596118

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