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A pocket-factor–triggered conformational switch in the hepatitis B virus capsid
Viral hepatitis is growing into an epidemic illness, and it is urgent to neutralize the main culprit, hepatitis B virus (HBV), a small-enveloped retrotranscribing DNA virus. An intriguing observation in HB virion morphogenesis is that capsids with immature genomes are rarely enveloped and secreted....
Autores principales: | Lecoq, Lauriane, Wang, Shishan, Dujardin, Marie, Zimmermann, Peter, Schuster, Leonard, Fogeron, Marie-Laure, Briday, Mathilde, Schledorn, Maarten, Wiegand, Thomas, Cole, Laura, Montserret, Roland, Bressanelli, Stéphane, Meier, Beat H., Nassal, Michael, Böckmann, Anja |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092406/ https://www.ncbi.nlm.nih.gov/pubmed/33879615 http://dx.doi.org/10.1073/pnas.2022464118 |
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