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Replacement of S14 Protein in Ribosomes of Zinc-Starved Mycobacteria Reduces Spectinamide Sensitivity

Zinc is an essential micronutrient for mycobacteria, and its depletion induces multiple adaptive changes in cellular physiology, the most remarkable of which are remodeling and hibernation of ribosomes. Ribosome remodeling, induced upon relatively moderate depletion of zinc, involves replacement of...

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Detalles Bibliográficos
Autores principales:	Li, Yunlong, Koripella, Ravi K., Sharma, Manjuli R., Lee, Richard E., Agrawal, Rajendra K., Ojha, Anil K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Mechanisms of Resistance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092523/ https://www.ncbi.nlm.nih.gov/pubmed/33361293 http://dx.doi.org/10.1128/AAC.01833-20

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