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A nanobody toolbox targeting dimeric coiled-coil modules for functionalization of designed protein origami structures
Coiled-coil (CC) dimers are widely used in protein design because of their modularity and well-understood sequence–structure relationship. In CC protein origami design, a polypeptide chain is assembled from a defined sequence of CC building segments that determine the self-assembly of protein cages...
Autores principales: | Majerle, Andreja, Hadži, San, Aupič, Jana, Satler, Tadej, Lapenta, Fabio, Strmšek, Žiga, Lah, Jurij, Loris, Remy, Jerala, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092592/ https://www.ncbi.nlm.nih.gov/pubmed/33893235 http://dx.doi.org/10.1073/pnas.2021899118 |
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