Cargando…

Pathophysiological Mechanisms and Experimental Pharmacotherapy for L-Dopa-Induced Dyskinesia

L-dopa-induced dyskinesia (LID) is the most frequent motor complication associated with chronic L-dopa treatment in Parkinson’s disease (PD). Recent advances in the understanding of the pathophysiological mechanisms underlying LID suggest that abnormalities in multiple neurotransmitter systems, in a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fabbrini, Andrea, Guerra, Andrea
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092630/ https://www.ncbi.nlm.nih.gov/pubmed/33953618 http://dx.doi.org/10.2147/JEP.S265282

Ejemplares similares

Corticostriatal Plastic Changes in Experimental L-DOPA-Induced Dyskinesia
por: Ghiglieri, Veronica, et al.
Publicado: (2012)

Opioid system in L-DOPA-induced dyskinesia
por: Pan, Jing, et al.
Publicado: (2017)

Circuit Mechanisms of L-DOPA-Induced Dyskinesia (LID)
por: Yang, Kai, et al.
Publicado: (2021)

Inhaling xenon ameliorates l‐dopa‐induced dyskinesia in experimental parkinsonism
por: Baufreton, Jérôme, et al.
Publicado: (2018)

On the neuronal circuitry mediating l-DOPA-induced dyskinesia
por: Cenci, M. Angela, et al.
Publicado: (2018)

Maladaptive Synaptic Plasticity in L-DOPA-Induced Dyskinesia
por: Wang, Qiang, et al.
Publicado: (2016)

Presynaptic Mechanisms of l-DOPA-Induced Dyskinesia: The Findings, the Debate, and the Therapeutic Implications
por: Cenci, M. Angela
Publicado: (2014)

Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice
por: Shi, Ziqing, et al.
Publicado: (2020)

Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia
por: Navailles, Sylvia, et al.
Publicado: (2012)

Dopamine D3 Receptor Plasticity in Parkinson’s Disease and L-DOPA-Induced Dyskinesia
por: Lanza, Kathryn, et al.
Publicado: (2021)

L-dopa-induced dyskinesia: beyond an excessive dopamine tone in the striatum
por: Porras, Gregory, et al.
Publicado: (2014)

Striatal Plasticity in L-DOPA- and Graft-Induced Dyskinesia; The Common Link?
por: Rylander Ottosson, Daniella, et al.
Publicado: (2016)

Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia
por: Bastide, Matthieu F., et al.
Publicado: (2017)

L-DOPA-Induced Dyskinesia in a Genetic Drosophila Model of Parkinson’s Disease
por: Blosser, Joshua A., et al.
Publicado: (2020)

The Vasomotor Response to Dopamine Is Altered in the Rat Model of l‐dopa‐Induced Dyskinesia
por: Booth, Samuel, et al.
Publicado: (2020)

Eltoprazine modulated gamma oscillations on ameliorating L‐dopa‐induced dyskinesia in rats
por: Bi, Yuewei, et al.
Publicado: (2023)

Predictors of Levo-dopa induced Dyskinesias in Parkinson's Disease
por: Athulya, RT, et al.
Publicado: (2020)

Interactions between Angiotensin Type-1 Antagonists, Statins, and ROCK Inhibitors in a Rat Model of L-DOPA-Induced Dyskinesia
por: Lopez-Lopez, Andrea, et al.
Publicado: (2023)

Mass spectrometry imaging identifies abnormally elevated brain l-DOPA levels and extrastriatal monoaminergic dysregulation in l-DOPA–induced dyskinesia
por: Fridjonsdottir, Elva, et al.
Publicado: (2021)

Role of Serotonin Neurons in L-DOPA- and Graft-Induced Dyskinesia in a Rat Model of Parkinson's Disease
por: Shin, Eunju, et al.
Publicado: (2012)

Signal transduction in l-DOPA-induced dyskinesia: from receptor sensitization to abnormal gene expression
por: Spigolon, Giada, et al.
Publicado: (2018)

An Integrative Approach to Treat Parkinson's Disease: Ukgansan Complements L-Dopa by Ameliorating Dopaminergic Neuronal Damage and L-Dopa-Induced Dyskinesia in Mice
por: Huh, Eugene, et al.
Publicado: (2019)

The Role of the Subthalamic Nucleus in L-DOPA Induced Dyskinesia in 6-Hydroxydopamine Lesioned Rats
por: Aristieta, Asier, et al.
Publicado: (2012)

Untangling Cortico-Striatal Connectivity and Cross-Frequency Coupling in L-DOPA-Induced Dyskinesia
por: Belić, Jovana J., et al.
Publicado: (2016)

Polymorphisms of Dopamine Receptor Genes and Risk of L-Dopa–Induced Dyskinesia in Parkinson’s Disease
por: Comi, Cristoforo, et al.
Publicado: (2017)

Basal ganglia neuropeptides show abnormal processing associated with L-DOPA-induced dyskinesia
por: Hulme, Heather, et al.
Publicado: (2022)

Phosphodiesterase 10A Inhibition Modulates the Corticostriatal Activity and L-DOPA-Induced Dyskinesia
por: Guimarães, Rayanne Poletti, et al.
Publicado: (2022)

7-Nitroindazole reduces L-DOPA-induced dyskinesias in non-human Parkinsonian primate
por: Herrero, M. T., et al.
Publicado: (2023)

Behavioral effects of zonisamide on L-DOPA-induced dyskinesia in Parkinson's disease model mice
por: Sano, Hiromi, et al.
Publicado: (2023)

Serotonergic system modulation holds promise for L-DOPA-induced dyskinesias in hemiparkinsonian rats: A systematic review
por: Farajdokht, Fereshteh, et al.
Publicado: (2020)

Serotonin System Implication in l-DOPA-Induced Dyskinesia: From Animal Models to Clinical Investigations
por: Carta, Manolo, et al.
Publicado: (2014)

Spontaneous locomotor activity and L-DOPA-induced dyskinesia are not linked in 6-OHDA parkinsonian rats
por: Sgroi, Stefania, et al.
Publicado: (2014)

Cell type-specific plasticity of striatal projection neurons in parkinsonism and L-DOPA-induced dyskinesia
por: Fieblinger, Tim, et al.
Publicado: (2014)

Differential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia
por: Bido, Simone, et al.
Publicado: (2015)

Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study
por: Svenningsson, Per, et al.
Publicado: (2015)

Modulation by Estradiol of L-Dopa-Induced Dyskinesia in a Rat Model of Post-Menopausal Hemiparkinsonism
por: Kolmančič, Kaja, et al.
Publicado: (2022)

D2R signaling in striatal spiny neurons modulates L-DOPA induced dyskinesia
por: Florio, Ermanno, et al.
Publicado: (2022)

Enhanced histamine H2 excitation of striatal cholinergic interneurons in L-DOPA-induced dyskinesia
por: Lim, Sean Austin O., et al.
Publicado: (2015)

Broad Serotonergic Actions of Vortioxetine as a Promising Avenue for the Treatment of L-DOPA-Induced Dyskinesia
por: Budrow, Carla, et al.
Publicado: (2023)

Levetiracetam Ameliorates L-DOPA-Induced Dyskinesia in Hemiparkinsonian Rats Inducing Critical Molecular Changes in the Striatum
por: Du, Huan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_hcj8cjv9k6317bnbj99jfc8c1j