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Assessment of carbapenems in a mouse model of Mycobacterium tuberculosis infection

We present further study of a subset of carbapenems, arising from a previously reported machine learning approach, with regard to their mouse pharmacokinetic profiling and subsequent study in a mouse model of sub-acute Mycobacterium tuberculosis infection. Pharmacokinetic metrics for such small mole...

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Detalles Bibliográficos
Autores principales:	Jadhav, Ravindra, Gallardo-Macias, Ricardo, Kumar, Gaurav, Daher, Samer S., Kaushik, Amit, Bigelow, Kristina M., Nuermberger, Eric L., Lamichhane, Gyanu, Freundlich, Joel S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092647/ https://www.ncbi.nlm.nih.gov/pubmed/33939697 http://dx.doi.org/10.1371/journal.pone.0249841

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