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A structural signature motif enlightens the origin and diversification of nuclear receptors

Nuclear receptors are ligand-activated transcription factors that modulate gene regulatory networks from embryonic development to adult physiology and thus represent major targets for clinical interventions in many diseases. Most nuclear receptors function either as homodimers or as heterodimers. Th...

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Detalles Bibliográficos
Autores principales: Beinsteiner, Brice, Markov, Gabriel V., Erb, Stéphane, Chebaro, Yassmine, McEwen, Alastair G., Cianférani, Sarah, Laudet, Vincent, Moras, Dino, Billas, Isabelle M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092661/
https://www.ncbi.nlm.nih.gov/pubmed/33882063
http://dx.doi.org/10.1371/journal.pgen.1009492