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The Immunological Impact of Adenovirus Early Genes on Vaccine-Induced Responses in Mice and Nonhuman Primates
Adenovirus (Ad) is being explored for use in the prevention and treatment of a variety of infectious diseases and cancers. Ad with a deletion in early region 3 (ΔE3) provokes a stronger immune response than Ad with deletions in early regions 1 and E3 (ΔE1/ΔE3). The ΔE1/ΔE3 Ads are more popular becau...
Autores principales: | Sangare, Kotou, Tuero, Iskra, Rahman, Mohammad Arif, Hoang, Tanya, Miller-Novak, Leia K., Vargas-Inchaustegui, Diego A., Venzon, David J., LaBranche, Celia, Montefiori, David C., Robert-Guroff, Marjorie, Thomas, Michael A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092689/ https://www.ncbi.nlm.nih.gov/pubmed/33441339 http://dx.doi.org/10.1128/JVI.02253-20 |
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