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Coronavirus Endoribonuclease Ensures Efficient Viral Replication and Prevents Protein Kinase R Activation

Coronavirus (CoV) nsp15 is an endoribonuclease conserved throughout the CoV family. The enzymatic activity and crystal structure of infectious bronchitis virus (IBV) nsp15 are undefined, and the protein’s role in replication remains unclear. We verified the uridylate-specific endoribonuclease (EndoU...

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Detalles Bibliográficos
Autores principales:	Zhao, Jing, Sun, Lu, Zhao, Ye, Feng, Delan, Cheng, Jinlong, Zhang, Guozhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Virus-Cell Interactions
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092692/ https://www.ncbi.nlm.nih.gov/pubmed/33361429 http://dx.doi.org/10.1128/JVI.02103-20

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