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The Intact Noninducible Latent HIV-1 Reservoir Is Established in an In Vitro Primary T(CM) Cell Model of Latency

The establishment of HIV-1 latency has hindered an HIV-1 cure. “Shock and kill” strategies to target this reservoir aim to induce the latent provirus with latency-reversing agents (LRAs). However, recent studies have shown that the majority of the intact HIV-1 viral reservoir found in antiretroviral...

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Detalles Bibliográficos
Autores principales:	Sarabia, Indra, Huang, Szu-Han, Ward, Adam R., Jones, R. Brad, Bosque, Alberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2021
Materias:	Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8092701/ https://www.ncbi.nlm.nih.gov/pubmed/33441346 http://dx.doi.org/10.1128/JVI.01297-20

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